Clinical Pediatrics

Biography

Biography: Flora Selimi

Abstract

 Introduction: Lymphoma is the most common blood cancer. The two main forms of lymphoma are Hodgkin lymphoma (HL) and non-Hodgkin Lymphoma

Purpose:Different types of NHL- Patterns of spread in different types of NHL-Initial diagnostics in suspect NHL-Risks associated with different typesof NHL-Possibilites for treatment and potential  outcomes-

Presentation of the case with Burkitt Lymphoma, which treatment in our ward.

Burkitt  lymphoma (BL)  is  an  uncommon form  of non-Hodgkin lymphoma.Burkitt's lymphoma is an aggressive B-cell form of NHL that occurs most often in children and young adults. BL named after British surgeon Denis Burkitt, who first  identified  this  unusual disease in  1956  among  children  in  Africa.The disease may affect the jaw, central nervous system, bone marrow, bowel, kidneys, ovaries or other organs. There are three main types of Burkitt lymphoma: (sporadic, endemic, and immunodeficiency related). Ly  Burkit  affects the third most  common childhood cancer.It occurs most  often in children between the ages of 7 and 11, but can occour at any ages from infancy to adulthood.Its affects males almost three times more often than female.

Burkit  lymphoma may be treated with   chemotherapy, radiation therapy, or autologus  stem cell transpation. Burkitt's lymphoma is potentially curable.  Presentation of the case with Lymphoma  Burkit, which was presented  to Hematology Oncology Unit at Pediatric Clinic  and  has  received chemotherapy treatment..

Materials and methods:  A male child,6 years old ,child comes to our clinic with abdominal pain,loss of apetite, fatigue, nights sweats and fever.After the examinations of: anamnesis, laboratory-hematology analysis, biochemical, RTG chest, USG  and CT  neck,chest, abdomen, pelvic  After  Ct examination  in conclusion :Ct  thorax (is not  represents the mediastinal  and axillar  lymph nodes) and Ct abdominal ( lymhonodes mesenterialis ), we prefer the biopsy and immunochemistry  The obtained results from pathology  proves  Lymphoma Burkitt .

Results.After the diagnosis it was indicated  the treatment protocol of chemotherapy for Burkitt Lymphomas  R-CHOP 21 (Rituximab, VCR, Doxorubicine, Cyclophosphamide, Prednisolon)  for 6 cycles.The  child was admitted in our ward, to  start and continue chemotherapy, the treatment was continued by doctors in our ward.Monitoring of his disease, continuing chemotherapy,laboratory chest, radiological images (CT  neck, chest, abdomen, pelvic),  are made by our ward,institute of University Clinical Center of Kosovo.

Conclusion: The resection of the lymphonodes, application of protocol RCHOP -21, supportive care,,monitoring of chemotherapy  toxicity,  has resulted in absence of minimal residual disease which confirmed by the follow up of his clinical status, laboratory tests, radiology images (PET scan),  that  resulted the absence of secondary deposits.Now  the child is a good health condition, and visits  our  clinic to follow up his condition.